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Diving into the minds of musicians to uncover new learning strategies

Pierre Legrain
Pierre Legrain
CNRS Research Director in perception and memory at Institut Pasteur

When study­ing the brain, neuro­bi­o­lo­gists tend to focus on the struc­ture and physiolo­gic­al func­tions of our body’s most vital organ. Hom­ing in on the dif­fer­ent cells (namely, neur­ones and glia) sci­ent­ists study the ways in which they inter­act through neur­al net­works and chem­ic­al mes­sages in the form of neur­o­trans­mit­ters (sero­ton­in, dopam­ine, adren­aline etc.). And how, bio­lo­gic­ally, the mul­ti­far­i­ous com­pon­ents of this cereb­ral orches­tra har­mon­ise as one. How­ever, they do less often study the thoughts gen­er­ated by these bio­chem­ic­al and physiolo­gic­al elements. 

As such, bio­lo­gist Prof. Pierre Legrain (Insti­tut Pas­teur) is tak­ing a rather uncon­ven­tion­al approach to study the human mind to uncov­er how the brain learns new things.  Con­trary to stand­ard prac­tise, he uses a hol­ist­ic phe­nomen­o­lo­gic­al exper­i­ment that con­sists of sim­ul­tan­eously col­lect­ing exper­i­ment­al data on per­cep­tion and indi­vidu­al reports from test sub­jects through intro­spect­ive inter­views. He asks the ques­tion: what does a per­son exper­i­ence when his/her brain per­forms spe­cif­ic functions? 

Learning to learn

“There are chil­dren for whom teach­ing meth­ods we use today do not work,” he announces. “I mean, there are a lot of kids who have learn­ing dif­fi­culties, and we tend to think that these kids aren’t ‘good’ at school. Yet, there is a lot of evid­ence to sug­gest that it is the way we teach these chil­dren that needs to be adap­ted – it’s not their fault.” 

He is refer­ring to learn­ing skills that, he says, most of us take for gran­ted. Pre­vi­ous work sug­gests that many chil­dren who are strug­gling in the edu­ca­tion­al sys­tem do so because they have not mastered the men­tal strategies neces­sary to suc­ceed in school. As a res­ult, many of those who struggle to learn the basics of read­ing, math, or even social skills, may simply be lack­ing cog­nit­ive abil­it­ies that can, in fact, be learnt. 

“For example, when you hear or see things in your mind and relate those ideas to the real world, you are improv­ing your cog­nit­ive abil­it­ies. This pro­cess is impli­cit and seems obvi­ous to many of us, but it is not obvi­ous for every­one,” he says.  Legrain works closely with his col­league Alain Letail­leur, a  spe­cial­ised teach­er for pupils with severe learn­ing dif­fi­culties, who has examined these the­or­ies on those chil­dren. In doing so, he had pre­vi­ously helped chil­dren learn to bet­ter use their brains by pick­ing up cog­nit­ive strategies such as men­tal visu­al, aud­it­ory or kin­aes­thet­ic asso­ci­ations, such as com­bin­ing a math­em­at­ic­al oper­a­tion with the ges­ture made on the calculator. 

Legrain and Letail­leur there­fore seek to bet­ter under­stand what learn­ing strategies are pos­sible in order to offer them to chil­dren with learn­ing difficulties. 

Musicians under the microscope

To study what hap­pens to the brain as it learns – in terms of thoughts, not in a dir­ectly bio­lo­gic­al sense – they are using musi­cians as test sub­jects. Under con­trolled con­di­tions, they played them a music­al note, which they then had to identi­fy as quickly as pos­sible. “In gen­er­al, they respond almost imme­di­ately,” he points out. It’s an import­ant factor because the test relies on the logic that the sub­jects all hear exactly the same thing and identi­fy it as the same note. There­fore, the input and out­put of the brain are as con­stant as it can get. 

The only thing that changes, there­fore, is the thought that occurs in the musician’s mind. He con­tin­ues, “after the response, we asked them to describe what they felt when their brain iden­ti­fied the note.” They did this in dif­fer­ent ways, some­times using a draw­ing to form­al­ise the idea. Inter­est­ingly, the musi­cians described a vari­ety of exper­i­ences – many of which were very dif­fer­ent from one anoth­er. Amongst them were descrip­tions of vibra­tions, images, asso­ci­ation with emo­tions, their music­al instru­ments, bod­ily responses or more, allow­ing the team to cre­ate a col­lec­tion of dif­fer­ent men­tal strategies used by their test subjects.

Examples of responses from study par­ti­cipants (musi­cians) who were asked to describe how they « knew » which note was being played (adap­ted from1).

Non­ethe­less, the key find­ing came from com­par­ing the two dis­tinct groups in the sample of musi­cians they stud­ied. He explains, “on the one hand, we had music stu­dents and on the oth­er, pro­fes­sion­al musi­cians. The men­tal mech­an­isms described by the stu­dents ten­ded to be related to learn­ing strategies, where­as the pro­fes­sion­als used thoughts more related to their artist­ic prac­tice, such as the instru­ment they play.” Hence, with a musician’s ‘expert­ise’ or pro­fi­ciency in their craft, the sub­jects seemed to have developed their own per­son­al­ised men­tal strategy for identi­fy­ing music­al notes. “We named these men­tal anchor­points [appuis men­taux, in French].” 

From the music hall to the classroom 

The next step will be quite com­plic­ated because it means tak­ing sev­er­al musi­cians who use dif­fer­ent men­tal anchor­points and study­ing them togeth­er. “We are now examin­ing the dif­fer­ent strategies used in the hopes of object­ively clas­si­fy­ing them. We will then need to find a way to spe­cific­ally inter­fere with one or anoth­er men­tal anchor­point to spe­cific­ally pre­vent a musi­cian from recog­nising the note.” 

This approach is nov­el in that it attempts to link bio­lo­gic­al find­ings to the psyche, which has rarely been stud­ied until now, so the chal­lenge is there. To bridge this gap, the team will com­bine their find­ings with neuroima­ging to identi­fy the neur­al cir­cuits that are involved. “We would like to be able to bet­ter char­ac­ter­ise these men­tal anchor­points in order to find effect­ive ways to apply them to aca­dem­ic learning.” 

Interview by James Bowers
1https://​www​.fron​ti​ersin​.org/​a​r​t​i​c​l​e​s​/​1​0​.​3​3​8​9​/​f​p​s​y​g​.​2​0​2​0​.​0​1​4​8​0​/full

Contributors

Pierre Legrain

Pierre Legrain

CNRS Research Director in perception and memory at Institut Pasteur

Pierre Legrain has published over 80 scientific articles. After a PhD in genetics and immunology, he focused his research at the Institut Pasteur in molecular and cell biology, more specifically developing a method for the exploration of protein-protein interactions at a large scale. Based on this technology, he co-founded in 1998 the first pasteurian biotech company, Hybrigenics, where he served as scientific director for five years. He also participated over fifteen years to the Human Proteome Organization (HUPO) where he has been in charge of the implementation of the worldwide Human proteome project. He joined the Ecole Polytechnique as Dean of the Graduate School (2011-2014) before returning to the Institut Pasteur as Executive VP development (2014-2017). Since 2018, he is back to full-time research activity with a project, Intermuse, dealing with biological inheritance and cultural transmission.

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